I have experimented with different settings and found the closer the boot sits to the center, the more stress it put on my ankles when kiteskating.
Remember that you are in a different position when kiting than regular skating.
Try this... tie a short rope to a tree (10 foot or so), grab the end and stand sideways to the tree with your knees bent and shoulders forward, then
lean your body away from the tree at about 30 to 45 degrees with most of your weight on the tree-side leg... how do your skates feel? This is about
the position you'll be skating in.
Of course, every kiteskater has different comfort points so each one should experiment to find the sweet spot. I offer the Doomwheels settings as a
verified starting point. Let us know if you settle on another.